The documentation about the history of San Jerónimo is fortunately very abundant, detailed, and reliable, as this is one of the historically most important municipalities in the department of Antioquia.

As time passed, by 1757, the Antioquia government created by decree the party of San Jerónimo de los Cedros, a date considered official as the founding of the municipality.

San Jerónimo is bordered by the following municipalities: Currently, San Jerónimo has acquired a new life and very broad opportunities for tourism, real estate business, and various economic sectors have opened up after the inauguration of the Fernando Gómez Martínez Tunnel, an engineering work that has halved the travel time between the capital of the department of Antioquia, Medellín, and this district.

Besides its municipal capital, San Jerónimo is composed of the following hamlets: Total Population: 15,361 (2018) Urban Population: 6,704 Rural Population: 8,657 Literacy Rate: 86.3% (2005) Urban Zone: 93.8% Rural Zone: 82.9% According to figures presented by DANE from the 2005 census, the ethnographic composition of the municipality is:[3] In addition to traditional national and international cuisine, demanded by the intense tourism, San Jerónimo offers, among other dishes, a curious local dish prepared with pig's blood and the pig's small intestine which is filled with rice, called "Morcilla."

Rice is cooked in the pig's blood, various seasonings are added, and this mixture is used to fill the small intestine after being cleaned.