The Palace is located in the countryside, 23 kilometres (14 mi) from the city of Concepción del Uruguay, in the province of Entre Ríos.
The archives treasure important historical documents, antiques, paintings of Urquiza's battles, and even manifests of ships that landed on Concepción's port.
The Palace served as a political stage; here, foreign diplomats were hosted and international treaties were signed.
Urquiza was assassinated in the Palace on the night of 11 April 1870 by followers of Ricardo López Jordán, a federal dissident.
The bloodied prints of Urquiza's hand are preserved in the room where this took place, which was then turned into an oratorium by his wife.