San Lorenzo is a comune (municipality) in the Province of Reggio Calabria in the Italian region Calabria, located about 120 kilometres (75 mi) southwest of Catanzaro and about 20 kilometres (12 mi) southeast of Reggio Calabria.

San Lorenzo borders the following municipalities: Bagaladi, Condofuri, Melito di Porto Salvo, Montebello Ionico, Roccaforte del Greco.

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