San Luis is a municipality and town in the Pinar del Río Province of Cuba.

It is centered mainly on agriculture (tobacco, rice, fruit crops), stock raising.

It was founded in 1827,[1] and established as a municipality in 1879, when it split from San Juan y Martínez.

Until 1977, its territory included the seaport village of La Coloma, currently part of Pinar del Río.

[4] The municipality is located west of Pinar del Río and includes the villages of Barbacoa, Barrigonas, Buenavista, El Corojo, El Retiro, Llanadas, Palizada, Santa María and Tirado.