The event consisted of over 1,000 emerging and 32 established artists competing over a five-month period from October 2022 through February 2023 for the opportunity to represent the nation at the contest.

Promotion of the entry consisted of the release of a music video as well as a tour of a selection of nations participating in the contest, including England, Israel, Poland, Spain, and the Netherlands.

[1] The nation's debut entry in the 2008 contest, "Complice" performed by Miodio, failed to qualify for the final and placed last in the semi-final it competed in.

[5] Her 2021 song, "Adrenalina", which she performed alongside American rapper Flo Rida, qualified for the final, eventually placing 22nd out of the 26 entries.

Artists who proceeded to the next round attended an academy in the Teatro Titano in the City of San Marino from 28 October 2022 and 16 February 2023, acting as preliminary castings.

[10] As the end of the auditions period approached, a special in-depth show, narrated by Maria Letizia Camparsi and focused on introducing and recapping Una voce per San Marino, was aired on RTV on 24 January 2023.

[13] By 14 October 2022, the broadcaster announced it had received over 400 applications, particularly from Spain, Germany and Norway, but also from other European countries, Canada, the United States and Australia.

[14] Near the close of the submission period, SMRTV reported that they had received over 1,000 applications overall from 31 different countries, out of which 299 were selected to take part in the emerging acts round.

[26] Interval acts included 2022's Sammarinese entrant Achille Lauro and 2008's Miodio, who marked 15 years since their performance for the nation's Eurovision debut.

The result was determined by a six-member jury panel consisting of Al Bano (jury president and Italy's 1976 and 1985 Eurovision entrant), Charlotte Davis (British television producer), Steve Lyon (British sound engineer), Clarissa Martinelli (journalist), Antonio Rospini (musician and artistic consultant), and Dino Steward (managing director of BMG Italy).

[26] The band Piqued Jacks consisted of Francesco Bini (bass), Andrea Lazzeretti (vocals), Tommaso Olivieri (drums), and Marco Sgaramella (guitar).

[31] Piqued Jacks' first live performance of "Like an Animal" following their selection took place on 25 March at an event held in Barcelona at the Palau Sant Jordi.

[32] Other promotional appearances took place in London, Tel Aviv, Madrid, Amsterdam, and Warsaw, the latter of which Piqued Jacks were joined by previous San Marino representative Senhit.

[32][33] The group also appeared in print media, having been interviewed about their participation and Eurovision journey by the Italian edition of Rolling Stone.

This jury judged each entry based on: vocal capacity; the stage performance; the song's composition and originality; and the overall impression by the act.

The Sammarinese jury consisted of Francesco Stefanelli, Lewis Busignani, Luca Zucchi, Barbara Andreini, and Sabrina Minguzzi.