The company is the Philippines’ largest brewery with a market share of over 95% as of 2008, notably producing San Miguel Beer.

Barretto was soon joined by Pedro Pablo Roxas as managing partner, who brought with him a German brewmaster, Ludwig Kiene, as technical director.

The company was renamed San Miguel Corporation (SMC) in 1963, having grown into one of the Philippines' largest business conglomerates with core interests in alcoholic and non-alcoholic beverages, food, and packaging.

On November 6, 2017, SMC announced the consolidation of its beverage businesses into San Miguel Pure Foods Company, Inc. through a share swap deal.

On January 2, 2013, trading of its stock was suspended when the rule on the minimum public ownership of listed shares took effect.