It is referred to in both Melchiori's and Venuti's guides as San Niccolò di Tolentino, and in the latter it adds the suffix a Capo le Case.

Starting in 1654, again with Pamphilj patronage, the church was rebuilt with designs by Giovanni Maria Baratta, one of the main pupils of Alessandro Algardi.

[4] In the third chapel on the right side is the sepulchral monument of Cardinal Federico Lante delle Rovere, with paintings by Pietro Paolo Baldini.

The cupola is frescoed (1643) by Pietro Paolo Baldini and depicts four female angels symbolising the four fundamental virtues of the Augustinian Order: Chastity, Humility, Poverty and Obedience.

[3] There is a memorial in the right side of the chapel of Saint Gregory the Illuminator; his cardinalitial hat hangs from the ceiling of the church.