San Salvador was the flagship of explorer Juan Rodríguez Cabrillo (João Rodrigues Cabrilho in Portuguese).
In 1540 the fleet sailed from Acajutla, El Salvador and reached Barra de Navidad, Mexico on Christmas Day.
While in Mexico, Pedro de Alvarado went to the assistance of the town of Nochistlán, which was under siege by hostile natives and was killed when his horse fell on him, crushing his chest.
Part of the fleet was sent off to the Philippine Islands under Ruy Lopez de Villalobos and two of the ships were sent north under the command of Cabrillo.
The ship was constructed in full public view at Spanish Landing park on Harbor Drive in San Diego.
The project gave people the opportunity to see an example of sixteenth century shipbuilding, which was the first modern industrial activity in the Americas.
However, on 8 April the ceremony was postponed due to "unanticipated technical complications involving the movement and lifting of the ship".
She made her public debut on 4 September 2015, leading a parade of tall ships for the start of San Diego's annual Festival of Sail.
A model of San Salvador was built by Señor Manuel Monmeneu in association with the Naval Museum of Madrid.