San Tomé is an oil company town, or camp, located about 8 miles northeast of the city of El Tigre, in the state of Anzoátegui in Venezuela.

[2] Ownership of San Tomé was assumed by Petróleos de Venezuela, Sociedad Anónima (PDVSA) after the oil industry was nationalized in 1975.

Campo Norte (North Camp) contains the regional headquarters of Petróleos de Venezuela, Sociedad Anónima (PDVSA), the country's state-owned oil and natural gas company.

[8] Campo Sur (South Camp) is a recreational area and includes workers' residences.

By 1940 a road and an oil pipeline had been constructed to connect El Tigre with Puerto La Cruz.

[3] This production occurred during World War II, when Venezuela was a major supplier of this critical commodity to the United States.

[2] Hollis Hedberg, an American geologist and petroleum scientist, was a primary contributor to Mene Grande's discoveries around El Tigre,[3] where he lived from 1937 to 1939.

After 1939 until 1946 he was based in San Tomé,[10] where he was in charge of all geological operations in eastern Venezuela for Mene Grande.

Hedberg later served as the chief geologist of Gulf Oil Company and was a professor of geology at Princeton University.

San Tomé was built as a service camp for Mene Grande in the late 1930s thru the 1950's on the model of a military base.

[20] After Venezuela nationalized the oil industry in 1975, PDVSA assumed ownership of San Tomé.

[21] By 2018 the political and economic troubles facing Venezuela had engulfed the El Tigre-San Tomé region.

[23] Emma Brossard commented in 2005, "Venezuelan oil fields had a depletion rate of 25 per cent annually [and] there had to be an investment of US$3.4 billion a year to keep up its production."

“But since Chavez has become president there has been no investment.”[17] The Anzoátegui campus of "La Universidad Nacional Experimental Politécnica de la Fuerza Armada Bolivariana" (The National Experimental Polytechnical University of the Bolivarian Armed Forces) (UNEFA) is located at San Tomé.