The church has ancient origins, but the first documented date is 1139, when Pope Innocent II consecrated it.

[2] In 1449, Pope Nicholas V granted the church to the Company of Scriptors and Copyists of the Curia.

[2] A "St. Thomas touching Jesus' side" and other paintings were stolen by the French during the occupation that followed the events of the Roman Republic.

The nave has a visible tile roof, while the outer aisles have plaster ceilings.

The high altar, set against the apse wall, has two marble columns on the sides and is crowned by a tympanon.

On the sides are paintings of Cardinal Gregorio Barbarigo and St Philip Neri.