There are currently 34 northbound vehicle lanes to cross from Mexico to the U.S.[5] [6] The southbound lanes of Interstate 5 which take vehicles into Mexico have been moved west of their previous location through the new El Chaparral Point of Entry (Spanish: Puerta México el Chaparral).

[7] This relocation and expansion was necessary to provide space for the construction of new administrative and border inspection facilities and to increase the number of northbound vehicle lanes.

[10] The PedWest pedestrian crossing is located at the east side of the Las Americas outlet mall where Virginia Avenue dead-ends at the border, immediately west of the El Chaparral port of entry into Mexico.

[15] By early 2021, the plaza on the Mexican side of PedWest had become a tent city populated by hundreds of asylum-seeking migrants waiting for their cases to be processed by the United States, causing the reopening of the crossing to be delayed indefinitely.

[16] Plans to re-open the crossing in December 2022 were halted following the United States Supreme Court's decision to maintain Title 42.

In the 1950s, due to congestion, truck traffic was moved a short distance west to a crossing at Virginia Avenue.

The current San Ysidro Land Port of Entry facility was constructed in the 1970s to meet the needs of the time and the projected growth in the coming years.

[18] On Sunday, November 25, 2018, groups of Central American migrants tried to forcibly cross the border into the United States.

Some of them threw rocks at US Border Patrol agents, who responded by firing tear gas into the crowd which included families with small children.

This was replaced when in August 2015 Mexico inaugurated a new pedestrian crossing facility to the east of the northbound traffic lanes.

[11] This walkway was nicknamed "Puente Chicanadas" ("cheap/quick fix bridge") and characterized by some as dangerous, suffocating and embarrassing to Mexico.