She is best known for her roles as Lavanya Kashyap in StarPlus romantic daily soap Iss Pyaar Ko Kya Naam Doon?

Her film career began in 2014 with the Telugu movie Dikkulu Choodaku Ramayya for which she adopted the screen name Sana Makbul.

[2] In this debut film, she played Samhitha, an aerobics trainer caught in a love triangle with a father and son.

[10] She then signed on for the Tamil crime thriller Rangoon directed by Rajkumar Periasamy, expanding her presence in the South Indian film industry.

[14] In June 2024, Makbul entered as a contestant in the third season of Bigg Boss OTT,[15] the Indian version of the reality TV show Big Brother.