She was married to Ferdinand I, the Count of Castile who later became King of León after having killed Sancha's brother in battle.

[8] Following Ferdinand's death in 1065 and the division of her husband's kingdom, she is said to have played the futile role of peacemaker among her sons.

[citation needed] She was a devout Catholic, who, with her husband, commissioned the crucifix that bears their name[9] as a gift for the Basilica of San Isidoro.

[3] She was interred in the Royal Pantheon of the Basilica of San Isidoro,[13] along with her parents, brother, husband, and her children Elvira, Urraca and García.

[14] The following Latin inscription was carved in the tomb in which were deposited the remains of Queen Sancha:[15] "H. R. SANCIA REGINA TOTIUS HISPANIAE, MAGNI REGIS FERDINANDI UXOR.