Sancti Spíritus Airport (IATA: USS, ICAO: MUSS) is an airport serving Sancti Spíritus,[1] the capital city of the Sancti Spíritus Province in Cuba.

The airport resides at an elevation of 90 m (295 ft) above mean sea level.

It has one runway designated 03/21 with an asphalt surface measuring 1,801 m × 29 m (5,909 ft × 95 ft).

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