Sandersdorf-Brehna is a town in the district of Anhalt-Bitterfeld, in Saxony-Anhalt, Germany.

The town was formed by the merger of the previously independent town Brehna and the municipalities Glebitzsch, Petersroda, Roitzsch and Sandersdorf, on 1 July 2009.

[3] The town Sandersdorf-Brehna consists of the following Ortschaften or municipal divisions:[4] The local council has 28 members, elections were held in May 2014.

Steffi Syska was elected mayor in October 2021.

[1] She succeeded Andy Grabner, who had been re-elected in April 2015 with 91.4% of the votes for a second term.