Sandra Ávila Beltrán (born 16 October 1960) is a Mexican drug lord, dubbed "La Reina del Pacífico" (The Queen of the Pacific) by the media.

[9] The police attribute her rise to power in the drug world primarily to her most recent relationship with Juan Diego Espinoza Ramírez, alias The Tiger, who is said to be an important figure in the Colombian Norte del Valle Cartel.

[9] Ávila Beltrán lived in Guadalajara, Jalisco, and Hermosillo, Sonora until the police found more than 9 tons of cocaine on a ship in the Pacific port of Manzanillo, Colima in 2001 and tracked the shipment to her and her lover Espinoza Ramírez.

"[18] In June 2012 several Mexican judges ruled out major obstacles to extradite Ávila Beltrán to the United States on cocaine trafficking charges that date back to 2001.

[18] On April 23, 2013, Avila Beltran pled guilty to being an accessory after the fact to the crime of drug trafficking, and on July 25 she was sentenced to 70 months in federal prison, with credit for time served.

At that time, she was processed to be administratively deported to Mexico as an aggravated felon, where she was immediately arrested on money laundering charges on 20 August 2013[22] and was sentenced to five more years in prison and a fine.

[25] She also published a book, The Queen of the Pacific: Time to Talk, based on a series of prison interviews she gave to Mexican journalist Julio Scherer.

[26] Arturo Pérez-Reverte, author of the book The Queen of the South (2002), stated that the story of his heroine Teresa Mendoza is partly based on Sandra Ávila Beltrán's life.

Los Tucanes de Tijuana wrote a folk ballad that pays homage to Sandra Ávila as "a top lady who is a key part of the business.