She continued to guest star in the 1950s and 1960s in such television series as I Love Lucy, I Married Joan,[2] December Bride, Maverick, The Flintstones, The Twilight Zone, The Lucy Show, Burke's Law, I Dream of Jeannie; Love, American Style; Gilligan's Island, The Brady Bunch and Mister Ed.

[1] In 1963, Gould released a comedy single record entitled Hello Melvin (This Is Mama) as an answer to Allan Sherman's hit "Hello Muddah, Hello Fadduh".

In September 1966, Gould replaced her friend[2] Alice Pearce, who had been battling ovarian cancer during the second season of the ABC-TV situation comedy Bewitched, and had died in March.

In the role of Gladys, Gould's over-the-top performance and shrill voice were popular with viewers, and she succeeded ultimately in making the character her own.

Gould also made appearances on Columbo, The Brady Bunch, Adam-12, Punky Brewster, Friends, and Veronica's Closet.