She is noted for her roles in the films The Left Ear (2015) and Soul Mate (2016), for which she won the Golden Horse Award for Best Leading Actress alongside her co-star Zhou Dongyu; and in television series Love Me If You Dare (2015) and Age of Legends (2018).

[2] Ma Sichun began her career as a child actress at age 7, when she appeared in The Winter of Three Persons, which stars Jiang Wenli and Zhao Jun.

[5] Ma achieved wider recognition after starring in the coming-of-age film The Left Ear, directed by Alec Su.

Her role as the rebellious and daring Li Bala received acclaim from critics and she was nominated as Best Supporting Actress at the Golden Horse Awards.

[10] In 2016, Ma starred in adventure film Time Raiders, based on the popular tomb-raiding novel series Daomu Biji.