Paños is recognised as one of Spain's best women's goalkeepers, winning a record four Zamora Trophies; with Barcelona she won the league, Copa de la Reina, Supercopa de España and UEFA Women's Champions League on multiple occasions.

The season following Ràfols' departure, she picked up a captaincy role for the first time in blaugrana and was named the club's third captain.

[16] In 2020, following the premature end of the 2019–20 league season due to the COVID-19 pandemic, Paños was awarded her fourth Zamora Trophy, a record number.

[18] In the quarterfinals of the UEFA Women's Champions League, Paños saved a penalty from Manchester City’s Chloe Kelly and recorded a clean sheet in a 3–0 win.

[21] Days after announcing her contract extension, she started the second Champions League final of her career and recorded a clean sheet against Chelsea, as the team won the match 4–0.

Paños was ineligible to win the Zamora Trophy however, as she suffered a thigh injury in October 2020 that kept her out of play for three months, and did not complete in at least 28 matches.

She still made appearances in all competitions, performing at a high level, and was recognised for not complaining about fewer minutes.

[30] On 23 June 2024, Liga MX Femenil side Club América announced the signing of Paños.

[32] In September 2011, she was called to Spain's senior national team for the first time, replacing injured María José Pons.

[38] Paños was among Las 15, the fifteen players who withdrew from international selection during a dispute with the Spanish federation in 2022; though reportedly being open to return for the 2023 World Cup, the coach had chosen a new starting goalkeeper during her absence and did not want to introduce tension in competing for the role, omitting Paños and calling up her Barcelona number two, Cata Coll instead.