Sandra Sumang Pierantozzi (born 9 August 1953) is a Palauan politician.

Pierantozzi was defeated by Camsek Chin in the 2 November 2004 vice-presidential election, winning only 28.9% of the vote.

Pierantozzi was born in Palau and holds degrees from San Diego State University, the University of Hawaii and Union College in Lincoln, Nebraska.

From 2009 to 2010 she was Minister of State, in charge of foreign and domestic affairs and international trade.

The special election in which Sandra Pierantozzi won was held in December 2015.