Alessandro "Sandro" Mazzinghi (3 October 1938 – 22 August 2020) was an Italian professional boxer who held the world light middleweight championship twice.

On 7 September 1963 he won the world light middleweight title, defeating the American Ralph Dupas by a ninth-round technical knockout in Milan.

Mazzinghi started again and gained the Superwelter European crown in Rome, Italy, on 17 June 1966 defeating Yoland Leveque; he defended his title four times.

On 26 May 1968, Mazzinghi beat Korean Ki-Soo Kim in "San Siro" Stadium, Milan, Italy, regaining the world light middleweight crown.

On 25 October he fought against American Freddie Little, but was disqualified by the referee for an illegal blow; this decision was revoked and the result of the match was changed to a "no contest".