Sangerhausen (German pronunciation: [zaŋɐˈhaʊzn̩]) is a town in Saxony-Anhalt, central Germany, capital of the district of Mansfeld-Südharz.

35 kilometres (22 miles) east of Nordhausen, and 50 km (31 mi) west of Halle (Saale).

Sangerhausen is mentioned as the tithable place Sangerhus in Friesenfeld in the Hersfeld Tithe Register, created between 881 and 899.

On 1 January 2005 the municipalities Gonna, Grillenberg, Horla, Lengefeld, Morungen, Obersdorf, Pölsfeld, Rotha and Wettelrode joined the association from the Verwaltungsgemeinschaft Südharz which was dissolved.

On the same date Breitenbach, Großleinungen and Wolfsberg also joined, coming from the municipal association Roßla-Südharz.