The river splits in two branches at the level of Khwaeng pagoda, 5 km (3.1 mi) south of Battambang city centre.

The Seksak Hydropower plant is located on the river near Traeng, approximately 45 km (28 mi) south-west of Battambang city.

However, in 2015, the lake level rise due to the dam was considered a menace to the touristic activities by local people.

In 2021, the province authorities investigated the potential chemical pollution of the river, after dead fish were found downstream.

[7] A ferry line connects Battambang city to Siem Reap, via the Sangkae river and the Tonle Sap Lake.