[1] The main panel shows the Baptism of Christ in the Jordan by John the Baptist, with the Holy Spirit descending in a gilded nimbus, angels assisting, saints around the scene and the heads of seraphim above.

[1] This probably corresponds to the side of the altarpiece which faces the church's nave: The monks caused very long delays, meaning that the predella was completed by Perugino's studio assistants using drawings by the artist himself.

The flanking panels of the saints show precise draughtsmanship as well as high detail in the flowers and small plants on the ground.

[2] The other side of the altarpiece faced the church's choir and work on its panels began in 1513, delivered at irregular intervals right up to Perugino's death.

[3] The rural backgrounds are very simple, with almost no flowers in the foreground to increase focus on the classically influenced figures, in which Perugino seems to have assimilated the style of his old pupil Raphael.