Sant'Eufemia a Maiella is a town and comune in the province of Pescara, Abruzzo, central Italy.

In the 14th century the town was renamed Santa Fumia and retained that name until 1863 when, by decree of King Victor Emmanuel II, it was named Sant'Eufemia a Maiella.

Until the 11th century Sant'Eufemia a Maiella was part of the Caramanico Terme.

Then, in 1064, Count Berardo gave the church of Sant'Eufemia and surrounding land at Caramanico to the Abbey of San Clemente a Casauria which retained possession of the town until 1145.

Eventually, in 1301 ownership was passed on to the Ughelli family and then to Giacomo Arcucci, the Count of Minervino.