Santa Bárbara is a town and municipality in the Colombian department of Antioquia.

Part of the subregion of Southwestern Antioquia.

Santa Barbara is located in a valley about 2.5 hours drive from Medellín by car or bus.

It lies at an elevation of 1,800 m (5,900 ft) above sea level.

This Department of Antioquia location article is a stub.