Santa Biondo (December 3, 1892, San Mauro Castelverde, Sicily – February 15, 1989, Stamford, Connecticut) was an American opera star whose career spanned from 1927 to 1938.

[8] The author of The Hartford Courant article described Biondo's voice as a "lyric-dramatic soprano, lyric for its 'facility of emission' and dramatic for its power and fullness of expression.

[10][11] One article, published in The Coshocton Tribune, claimed that the New York Police Department dredged the lake in Central Park, looking for her body.

[22] By September 1932, Santa Biondo was back on stage, singing in the title role in Aïda at Bryant Park for the Puccini Grand Opera Company.

The New York Times states that, in 1934, she sang in the role of Mimi in "La Bohème" for a throng of 5,000 at a Hippodrome National Opera Company event.

The September 22, 1929, edition of the Atlanta Constitution newspaper announced, "Santa Biondo, soprano with the Metropolitan Opera Company, will be the featured artist with an orchestra under the direction of Josef Pasternack in the broadcast of the Atwater Kent concert on the N.B.C.

[33] On April 29, 1934, she sang in the role of the Angel in the premier performance of Pietro Yon's "Triumph of Saint Patrick" at Carnegie Hall in New York City.

[38] After retiring from her career, Santa Biondo married Dr. Philip Giordano, advertising director of Il Progresso Italo-Americano newspaper and editor of Bolletino della Sera.

She is buried in the Biondo family plot in Saint Lawrence Cemetery located adjacent to the Yale Bowl in New Haven, Connecticut.