[1] It was first built in 1913 by the architect Aristide Leonori for Pope Pius X, in celebration of the 1600th anniversary of the Edict of Milan.

In the style of a Roman basilica, it has a mosaic-decorated facade, a portico with six Ionic columns and a mosaic by Biagio Biagetti, a five-storey bell tower and a three-aisled nave divided by six columns of Bavarian granite on each side.

It was opened for worship on 12 July 1914, and granted to the Congregation of the Sacred Stigmata (Stigmatines), but was not consecrated until 1918 (by Giuseppe Pallica, Titular Archbishop of Philippi).

In 1954, Pope Pius XII made it an alternative station church for Friday of the Fifth Week of Lent.

[1] The position of titular priest of the church is Sergio da Rocha since 19 November 2016.