is a small Roman Catholic chapel in Cangas de Onís, the first capital of the Kingdom of Asturias, in what is now northern Spain.

It was founded on an artificial mound (a pagan dolmen) by Favila, second king of Asturias, and his queen, Froiliuba.

It was begun in 737 and consecrated that same year on 27 October according to its original foundation stone, which has been called the first literary monument of the Reconquista.

[1] Santa Cruz originally housed the Cruz de la Victoria, an oak cross supposedly carried by Pelagius, Favila's father, at the Battle of Covadonga.

Then, local authorities decided to uncover the dolmen beneath it, which had been obscured by a church since the fourth century, when the first chapel was put up on that site.