Santa Cruz do Arari is a Brazilian municipality located in the state of Pará.

The city belongs to the mesoregion Marajó and the microregion of Arari.

[2] The United Nations HDI, or Human Development Index, score for Santa Cruz do Arari is 0.63.

[3] Nearby Lake Arari is a large lake located on the island Marajó, which is a tourist attraction and the home of a wide variety of avian life.

[4] The municipality is contained in the 59,985 square kilometres (23,160 sq mi) Marajó Archipelago Environmental Protection Area, a sustainable-use conservation unit established in 1989 to protect the environment of the delta region.