Santa Fé is a corregimiento and town in Chepigana District, Darién Province, Panama with a population of 6,923 as of 2010.

[1] It was created by Law 58 of July 29, 1998, owing to the Declaration of Unconstitutionality of Law 1 of 1982.

[1] It is approximately 200 km east of Panama City on the Inter-American Highway.

[2] The town contains a hospital.

This article about the geography of Darién Province is a stub.