Santa Giustina is a comune (municipality) in the province of Belluno in the Italian region of Veneto, located about 80 kilometres (50 miles) northwest of Venice and about 15 km (9 mi) southwest of Belluno.

Santa Giustina borders the following municipalities: Cesiomaggiore, Lentiai, Mel, San Gregorio nelle Alpi, Sedico, Sospirolo.

Mount Pizzocco is located nearby.

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