Santa María ("St. Mary" in Spanish) is a city and commune in the San Felipe de Aconcagua Province of central Chile's Valparaíso Region.

[2] According to the 2002 census of the National Statistics Institute, Santa María has 12,813 inhabitants (6,427 men and 6,386 women).

[2] As a commune, Santa María is a third-level administrative division of Chile, administered by a communal council (consejo comunal), which is headed by a directly elected alcalde.

The communal council has the following members:[1] Within the electoral divisions of Chile, Santa María is represented in the Chamber of Deputies by Marco Antonio Núñez (PDC) and Gaspar Rivas (RN) as part of the 11th electoral district, together with Los Andes, San Esteban, Calle Larga, Rinconada, San Felipe, Putaendo, Panquehue, Llaillay and Catemu.

The commune is represented in the Senate by Ignacio Walker Prieto (PDC) and Lily Pérez San Martín (RN) as part of the 5th senatorial constituency (Valparaíso-Cordillera).