Santa Maria di Loreto is a 16th-century church in Rome, central Italy, located just across the street from the Trajan's Column, near the giant Monument of Vittorio Emanuele II.

After the Jubilee of 1500, the association of bakers (Sodalizio dei Fornai) received permission from Pope Alexander VI to build a church at this site.

Construction of this church began in 1507 under Donato Bramante, carried out by Andrea Sansovino and completed by Antonio da Sangallo the younger.

The interior decoration is best noted for the statuary, including a statue at the entrance by Andrea Sansovino and around the altar, four angels by Stefano Maderno, and representations of four martyred virgin and Roman saints, apt companions to a church dedicated to the transposed house of the Virgin Mary's Annunciation.

[6] One chapel is covered by mosaics by Paolo Rossetti and was frescoed by the studio of Federigo Zuccaro.