Santa Sofia a Via Boccea (Ukrainian: Собор святої Софії, romanized: Sobor svyatoi Sofiy) is a church in Rome, Italy.

The Divine Liturgy is celebrated according to the Byzantine-Ukrainian rite, whilst still in full communion with the Catholic Church.

The church was built in 1967–1968 on the orders of Cardinal Josyf Slipyj, the Major Archbishop of Lviv, who had spent about 18 years in a Soviet gulag, and upon his release was not allowed to return to Ukraine.

Cardinal Mykola Bychok, Eparch of Saints Peter and Paul of Melbourne, holds the current title.

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