Settlements in Santaella date from as early as around 150,000 BC [citation needed].

Fertile countryside with good water supplies constituted the basis one where different towns and cultures arrive.

Among other inhabitants, the pre-Roman natives, the Roman civilization, the barbaric towns and the Hispanic-Moslem world outstand as relevant in Santaella actual configuration.

Then, Santaella was yielded to the Counsel of Cordoba by its son Alfonso X. Felipe II grants its jurisdictional independence, to pass, later, to be erected in marquisate, recovering its independence in 1735.

Among others, the Arabian walls, the homage tower and the Asuncion Church from the 17th century stand out for their relevance and beauty.