In 2012 he served as Minister of Social Development and Human Security in Yingluck Shinawatra cabinet, in the same year he attended the Coordinated Mekong Ministerial Initiative Against Trafficking meeting in Hanoi, Vietnam.

[1] On March 15, 2012, he was accused of slander by secretary of Human Development, Panita Kambhu na Ayutthaya.

[3] On January 17, 2014, he inspected human rights abuses at fishing industries after discovering that his country was placed on a black list by the Tier 2 Watch company for three years straight.

[4] On March 1, 2013, he, Minister of Labor Phadermchai Sasomsub, and Police General Adul Saengsingkaew have participated in a discussion on combating human trafficking which was hosted by Surapong Tovichakchaikul.

[6] In 2018, Santi moved to Palang Pracharath Party to form a government with Prime Minister Prayut Chan-o-cha.