Santiago (Spanish meaning Saint James) is a municipality of the western part of the state of Rio Grande do Sul, Brazil.

[2] Its elevation is 409 m. It is located 450 km west of the state capital of Porto Alegre and northeast of Alegrete.

Colonel José Maria Pereira de Campos created and organized the colony of Ijuí and brought Europeans to the area.

The Italians arrived in the 1880s, as the century passed, with the establishment of the colony of Jaguari, the localities of Sanga da Areia and Ernesto Alves.

In 1834, Arsene Isabelle, a French diplomat, in ways between the area, refers to a locality of Boqueirão de Santiago, its existence of three to four ranches.