Santiago Peak is a 6,522-foot-elevation (1,988-meter) summit in Brewster County, Texas, United States.

Although modest in elevation, topographic relief is significant as the summit rises 2,500 feet (762 m) above the surrounding terrain in 1.25 mile (2 km).

[8] This desert climate supports scrub brush, creosote bush, cacti, grasses, live oak, and mesquite growing on the slopes.

The mountain's toponym has been officially adopted by the United States Board on Geographic Names,[3] and has been reported in publications since at least 1902.

[9] Legend has it that the mountain was named after Santiago, an Indian fighter from Presidio del Norte who was killed by Apache at the base of this peak.