[1] It is a dense network of lympatics located in the dermis.
[2] The subareolar plexus of Sappey communicated with the plexus of lymph nodes located in the deep fascia of pectoralis major muscle.
[3] Subareoloar lympatic plexus is involved in the axillary spread of breast cancer to the surrounding organs.
[3] In 1874, the French anatomist Marie Philibert Constant Sappey discovered the subareoloar lympatic plexus by injecting mercury into the dermis of the breast of a cadaver.
Sappey's description became the theoritical basis for subareolar injection for lympatic mapping of the breast.