Sappho (also known as Mad Love) is a 1921 German silent film directed by Dimitri Buchowetzki and starring Pola Negri as the title character.

Richard De La Croix has a brother, Andreas, who has been driven insane by a notorious vamp and socialite named Sappho.

Sappho tries to return to Bertink but is turned away, so she seeks out Teddy, Richard's man-about-town friend, and starts a rebound relationship with him.

Meanwhile, Richard returns home to marry his childhood sweetheart, but then balks at the wedding supper and runs off in search of Sappho.

Richard finds Sappho at a ball with Teddy, and starts questioning her about her newest lover, before breaking down and admitting that she is the only woman he really loves.