Her mother (born 3 March 1954 in Fribourg, Switzerland) is a nurse who worked in Raja Isteri Pengiran Anak Saleha Hospital.

At Paduka Seri Begawan Sultan Science College (MSPSBS), she proceeded with her studies, finishing the lower secondary assessment in 2001 and the Brunei–GCE Ordinary Level in 2003.

[5] In November 2009, her performance in the third year of the Bachelor of Arts degree in Public Policy and Administration (English Stream) program earned her one of 140 Book Prizes.

[17] Their fourth child and second daughter, Pengiran Anak Faathimah Az-Zahraa' Raihaanul Bolkiah, was born at 15:54, on 1 December 2017.

At the launch of the Anti-Corruption Bureau's drama Code 486 on 2 April 2006, she emphasised that corruption is a country's internal enemy and urged young people to embrace patriotic ideals and refrain from anti-social behaviours.

[19] Additionally, at the inauguration of the 6th International School Brunei (ISB) Borneo Global Issues Conference (BGIC) on 1 March 2008, she stressed the significance of young people’s involvement in addressing global challenges, particularly environmental issues, and advocated for their active participation in finding solutions to these pressing problems, underscoring their vital role in shaping the future.

[20] On 17 May 2012, during the World Telecommunication and Information Society Day ceremony in Brunei, Pengiran Anak Sarah presented simulated certificates for ICT training to women's associations, aiming to enhance their technological skills, a crucial area for personal and professional growth in the modern world.

[22] Pengiran Anak Sarah’s dedication to youth development was further demonstrated on 10 March 2017, when she emphasised the importance of investing in young people for a sustainable future.

On 4 August 2024, she competed in the 5th Borneo Run Half Marathon, racing in the women's open division and covering a distance of 21.18 kilometres, before awarding prizes to the winners.

[27] Pengiran Anak Sarah is the royal patron of several organisations, including the Brunei Ladies Golf Association[28] and the ISB BGIC.