In her early career, Moyle portrayed roles in An Inspector Calls, Oliver!, Les Misérables and My Fair Lady.

She also made appearances in Drowning on Dry Land and Private Fears in Public Places, written for her by Sir Alan Ayckbourn.

[14] Following her exit from Doctors, Moyle appeared in an episode of the Britbox period series Sister Boniface Mysteries.

[19] In 2024, Moyle reunited with her former Doctors co-stars for an episode of the BBC programme Bargain Hunt.

[23] In September 2018, Moyle cycled 282 km across Rwanda[24] to raise money and awareness for Hope and Homes for Children.

She is also an advocate for the Alzheimer's Society, and ran the 2000 London Marathon to raise money for the charity.

[25] In 2020, Moyle raised money for the charity of which she is patron, Embracing Arts,[26] by cycling 46 miles around London.