Sarandí Grande is a city in the north of the Florida Department of central Uruguay.

It is located on the intersection of Route 5 with Route 42, about 140 kilometres (87 mi) from Montevideo, 43 kilometres (27 mi) north-northwest of Florida, the capital city of the department, and 43 kilometres (27 mi) south-southeast of Durazno, the capital city of the Durazno Department.

On 13 June 1906, its status was established as "Pueblo" (village) by the Act of Ley N° 3.042, at the time serving as head of the judicial section of "Estación Sarandí".

It was renamed "Sarandí" and its status was elevated to "Villa" (town) on 15 October 1923 by the Act of Ley N° 7.638.

[1] Finally, on 1 July 1956 it was renamed "Sarandí Grande" and its status was elevated to "Ciudad" (city) by the Act of Ley N° 11.960.