Sardis is a census-designated place (CDP) in southeastern Lee Township, Monroe County, Ohio, United States.

Sardis is at the intersection of Ohio State Routes 7 and 255, lying between Duffy and Fly.

Among the early settlers in this area was Major Earl Sproat, one of the 48 members of the Ohio Company.

This school is shared with other nearby riverfront communities including: Antioch, Duffy, Fly, Hannibal, Laings, Powhatan Point (of neighboring Belmont County), and Clarington.

[citation needed] According to the United States Census Bureau, the CDP has a total area of 1.2 square miles (3.2 km2), all of it land.