Satake Yoshimasa (佐竹義真, September 7, 1728 – September 17, 1753) was the 6th daimyō of Kubota Domain in Dewa Province, Japan (modern-day Akita Prefecture), and then 24th hereditary chieftain of the Satake clan.
He was received in formal audience by Shōgun Tokugawa Yoshimune in 1744, and became daimyō of Kubota in 1749.
Kubota Domain was rent by peasant uprisings and by plots among his retainers caused by the years of mismanagement of the domain by his predecessor.
Yoshimasa died at Kubota Castle in 1753 after complaining of sudden stomach pains and growing numbness in his limbs.
During the Edo period it was widely suspected that he had been poisoned.