The song is in common time throughout and follows the basic ABABCB skeleton, wherein 'A' is the verse, 'B' is the prechorus and chorus, and 'C' is the bridge.
The song's verses are in the key of C natural minor and feature a i-VI-III-VII progression repeated three times, with a chord change every two beats.
It shows the band members performing in an open space, and then cancer survivors are shown lying on the floor, gradually they rise, and at the end of the video, their names appear.
The video features band members' relatives who have survived cancer, and other cancer survivors such as Kevin Hearn, Sharon Osbourne, Marissa Jaret Winokur, René Angélil, Delta Goodrem, then Montreal Canadiens captain Saku Koivu and Bif Naked.
"Save You" debuted at #88 on the Canadian Hot 100 based on airplay alone, and rose up the chart each week up to the top forty.