A sequel, titled Shin Black Jack ni Yoroshiku, was serialized in Shogakukan's Big Comic Spirits magazine from January 2007 to July 2010, with its individual chapters being collected into nine volumes.

[5] A sequel, titled Shin Black Jack ni Yoroshiku (新ブラックジャックによろしく, Shin Burakku Jakku ni Yoroshiku), also written and illustrated by Satō, began serialization in Shogakukan's Big Comic Spirits magazine on January 22, 2007.

[8] In April 2012, Satō canceled his contract with Kodansha and warned that any remaining copies in bookstores were "illegal publications".

[9] In August, Satō began allowing free secondary use of the title, allowing people to "use the original work to create editions in foreign languages, films, applications, anime, and more without any royalty payments", effectively putting the series in public domain.

[13] A live-action television drama adaptation, with direction by Shunichi Hirano, scripts by Noriko Goto, and Satoshi Tsumabuki starring, was aired on TBS from April 11 to June 20, 2003.