Sayf al-Din Muhammad (Persian: سیف الدین محمد) was the king of the Ghurid dynasty from 1161 to 1163.
He was the son and successor of Ala al-Din Husayn.
After the accession of Sayf, he began persecution of the Ismailis who were favored during the reign of his father.
[1] With the aid of Ghiyath al-Din Muhammad, Sayf later waged war against the Oghuz Turks.
Sayf was betrayed and murdered during a battle in 1163 near Merv by a brother of the Ghurid general Warmesh ibn Shith, whom Sayf had executed.