Sayre is a borough in Bradford County, Pennsylvania, United States.

It is the principal city in the Sayre, PA Micropolitan Statistical Area.

[3] Sayre is part of the Penn-York Valley ("The Valley"), a group of four contiguous communities in New York and Pennsylvania: Waverly, New York; South Waverly, Pennsylvania; Sayre; Athens, Pennsylvania, and smaller surrounding communities with a combined population near 35,000.

Robert Heysham Sayre, president of the Pennsylvania and New York Railroad, helped cement the deal.

The Pennsylvania Guide, compiled by the Writers' Program of the Works Progress Administration, described Sayre in 1940 and emphasized the economic and social significance of the railroad, noting that Sayre:[4]was a small railway settlement until the Lehigh Valley Railroad constructed a roundhouse and shops here in 1871 and named the place for Robert H. Sayre, superintendent of the road.

On the left of the railroad tracks, which traverse the eastern section of the town, is a soot-blackened residential district.

The Lehigh Valley Railroad Shops ... devoted to maintenance, repairs, and storage, employ more than 1,200 men and completely dominate Sayre's existence.

Sayre is bounded on the east and west by Athens Township, on the south by the borough of Athens, on the northwest by South Waverly, and on the north by Waverly, New York.

Pennsylvania Route 199 passes through the borough as Keystone Avenue, Mohawk Street, and Spring Street, ending at Interstate 86 just over the state line in Waverly, New York.

BeST Transit makes numerous stops in Waverly, Sayre, and Athens and provides service to Towanda, Wysox, Troy, Canton, and the Lycoming Mall.

Children residing in the borough are assigned to attend the Sayre Area School District.

Community organizations: The "horned giants" of Sayre is an urban legend concerning a series of skeletons that included a horned skull reportedly discovered during the 1880s by the then-state historian, Dr. G.P.

[15][16] The skeletons were reported to be at or above 7 feet (2.1 m) in height, possessing skulls that had horn-like protuberances just above the eyebrows,[16] but were claimed to have been lost, misplaced, or stolen while en route to the American Investigation Museum.

[17][18] Neither Donehoo, Skinner, nor Moorehead described the discovery of any human skeletons at Sayre exhibiting gigantism or horned protrusions in their official excavation reports[19][20][21]